Natalie the Nerd is no stranger to Game Boy modding. As a PCB designer, she has already created the first completely transparent Game Boy motherboard, that can be retrofitted into an existing shell.
Not content with this world first, she has successfully managed to transplant the silicon from an actual Game Boy into the Lego Game Boy, making it capable of playing original Game Boy cartridges.
Considering the product was only available to purchase widely as of yesterday (1st October 2025), this makes the feat even more astounding. Natalie used the press photos to calculate the dimensions of the screen inserts, where more or less all the components are fitted. From there, a custom PCB was designed to host the CPU from a Game Boy Pocket (MGB) as opposed to an original DMG, largely due to the internal VRAM and need to save space.
The original Lego Game Boy actually comes with clickable buttons which Natalie wired in with a custom 3D printed Lego brick. The power circuit comes from one of her existing products, a "Safer Charging" board, which she sells via her shop and is already pretty miniscule.
The question on everybody's mind, is likely whether we will be able to do this ourselves? While at the moment the answer is probably no (unless you have a very special set of skills), Natalie promises to refine the board and release the full project once she is finished with it. The Lego Game Boy kit is currently available on Amazon if you want to snag one, in anticipation of attempting this yourself when she does.
Further details about the project can be found via her blog.